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If I apply pressure to the back of my neck, my neck pain still hurts really bad, but I can move my neck. It was becoming clear to me at this point that activity brought on my symptoms, and at that time it was extreme activity a session at the gym, a long bike ride, a strenuous walk. She is 86. oscar the grouch eyebrows. Both. Lately i have been feeling tooth pain and have told by the dentist they cannot see me without a letter from my GP if i am taking alendronic acid. My recent dexa scan showed a deterioration in bone loss in the last three years so much so that I now have osteoporosis in my hip. ). Then, they will assess if youll have to continue taking it or take a break from it by stopping the medication completely. I am 62. I was prescribed in 2003 following a crack in my Femur following a knee replacement and the resulting Dexa scan! Alendronate is also used to treat Paget's disease of bone. In a typical nanoconstruct, alendronic acid is conjugated with hydrophilic head moiety of phospholipid that has an ability to self-assemble with hydrophobic polymeric core through its hydrophobic long carbon-chain. As I was searching through my kitchen drawers, it came to me. I was intrigued as my doctor had said specifically not to! have been taking the drugs, with 3 years seen as a threshold point for an increased likelihood of adverse effects. Despite the doctors assurances that it wasnt addictive, I became addicted. My GP told me to take alendronic acid with the calcium and vit D tabs 5 or so years ago (in my mid 40s), after a DEXA scan showed I had mild osteoporosis already. I was told i had Oesteoporosis of the spine with high risk of a fracture. muscle cramps or spasms, a tingling sensation in your fingers or around your mouth - these can be symptoms of low calcium levels in your blood. Nothing too spectacular to report. This way, youll prevent any irritation in your throat or esophagus. I ran on a treadmill for twenty minutes and I could push my weight in kilos on the leg press. my Dr. told me she did not want me to take the Alendronic Acid because it would loosen my teeth. You can only stop taking alendronic acid when your doctor says so. My story begins in May 2014 when I was 72 and took the first once a week dose of one tablet with a glass of water. Its 2.35am here in Kent & I am terrified about what 2moro will bring if I am forced to use AA. Blood test in November showed a underactive thyriod and am taking Levothyronine 25mg. It knocked me out so I stopped it. This year the odd finger started my hands have started shaking when I am on my keyboard but for the past 3 months both hands shake. And dairy products reach in calcio. Hi Newsletter archive, Data Based Medicine Global Ltd. I was not aware until yesterday that Alendronic could be the cause. AA scares me to death as 4 months after taking it I seem to have a continues dry sort throat ( weirded really) so I feel I dont want to take it anymore at my age anyway 75. Im also having episodes of increased heart rate on a regular basis just from walking a short distance. The current protocol for this drug is for 3-5 years maximum. I was able to see a neurologist fairly quickly, and he concurred with my thoughts that it was probably Seroxat clashing with the anti-sickness tablets (metaclopromide) I had taken in September, and therefore a one-off event. I asked how we would know if it wasnt working, and his reply was that it would be having an effect on my bones after six months and the next scan results would indicate an increased bone density, or not. Ohh my Goodness thank you so much for your post. I would be grateful for any help or advice I have had OA in my lumber Thorasic and Cervical regions of my spine and also in both of my hips and was given a Bone density scan which showed the OA has progressed to Osteopena for this the consultant prescribed Alendronic Acid tablets 70mg which I take once a week from 30/03 /13 . Results are insufficient to support the use of alendronic acid in paediatric patients with osteogenesis imperfect. All Rights Reserved. I found it all extremely interesting and worrying. Stop taking your alendronic acid yes like you I been taking AA for about 2yrs in this time I have had a dry mouth enough to think Im going to lose all my teeth at the time . From day one I didnt believe that my body needed them but was told that When your taking steroids the additional meds are also needed & I was told this by more than one GP!!! So I still have not gotten ANY doctor to tell me that the osteo drugs were what CAUSED this but I dont see any other possible cause. Hi, my story is very similar but I only found out today that Alendronic Acid has caused my dental problems. Also does anyone know what element of AA gives you the aches and pains so that I know if it will be safer for me to take the Risedronate please? What is Alendronic acid 70mg tablets used for? DICE Dental International Congress and Exhibition. It is a condition when you have fragile bones, making you prone to bone fractures or breaks from daily activities such as walking or standing. Ive been on Alendronic Acid for about ten years, possibly longer. I reported the effect the drug had on me to the MHRA. When I showed this to my GP, he said that is not correct and the book was wrong. It may put you at risk of jaw bone damage. they mask the crumbling bones within and only show the outer bone growth, I have decided I really dont want to take these any more but wonder if there are side effects. I have also been taking Adcal tablets for years. My legs and bottoms of feet, are so painful. I Have been taking Alendronic Acid Tablets for 11 months now. Thank you. beyond distribution houston tx; bagwell style bowie; alex pietrangelo family; atlas 80v battery run time; I have been taking them for about 5 weeks. The Royal Osteoporosis Society website is very detailed and useful, with info on exercise you should do more of it which must be weight bearing more so than just walking and promote balance. There are dentists and oral surgeons in the US who will not treat people if they are on this drug. I asked her how long wil it take for the fosamax to leave my body, and when will this pain stop. Following a recent hip fracture and subsequent dexa scan, it was shown that I had Osteoporosis mainly in the right hip and spine (my hip fracture was on the left side ! Took dose 8 yesterday, and so far so good. Youre description of whip lash injury describes me. Ive only taken one tablet going to speak to Dr tomorrow. The NHS Dentist has ben very negative and created time consuming visits which are difficult for me to arrange because I have decreasing mobility because of MS. No one my GP or the dentist recommended by my GP have given me no warning about the serious side effects of having dental extractions while taking Aldronic Acid. If you are taking this tablet once a week . You uesly get shake from over active thyroid, I know because that what I have, I have been put on alendronic, I havent taken them yet, its very frigthening, not sure what to do, Im 63 and have gone to the gym most ofy life, I dont want to there guinea pig,. I am interested about the post that said you should only really take for 2 years does anyone else have info on this. To my surprise he agreed. Reading these reports,i am now worried.am 63 & After taking AA 70mg per wkfor 2months,& all the awful side effects mentioned here,consultant wants to try zoledronate yearly infusion. This settled after a few days She told me that all of these drugs, which is just a few, would cause me to have the same side effects. Its now Friday and still feeling joint pain all over my back, its lessened but it seems to have moved from my right to left side? September 2020 Diagnosed with PMR & prescribed Prednisolone + ADCAL3D +Alendronic Acid. My ears was hurting. I took Alendronic Acid for 6 months and stopped 5 months ago. I too am very healthy woman 67, play golf dance swim walk, so I was upset to be told I had osteoporosis. For alendronic acid Common or very common Gastrointestinal disorders; joint swelling; vertigo Uncommon Haemorrhage Rare or very rare Femoral stress fracture; oropharyngeal ulceration; photosensitivity reaction; severe cutaneous adverse reactions (SCARs) Side-effects, further information So after a bit of Internet research and finding this site, I will no longer be taking either drug. Dosage instructions, including remaining upright for at least 30 minutes and taking with a full glass of water, must be strictly followed. You can, however, lie down after youve eaten your first meal of the day. Learn more. About 3 hours later, I started to feel weird, sort of dizzy. Thanks. I also had pain/soreness behind the eyes and a niggling headache for 48 hours. After reading the comments I will not be taking it again. You can only take it with plain water, not mineral water. I am diary intolerant. Until this doctor expressed his surprise that I was taking it, and his opinion that it was possibly the cause of my problems, no one had ever raised any questions about it. Hi Judith Now, the only exercise I get is pottering around my house or gently along my local high street. But after a yr i got a very bad back, ended up a right angle for 6 wks, now i have just pushed hard with a screwdriver and got such a pain in my side. Im just another person looking for help with my bones, having been told by my doctor that there is no alternative to Alendronic Acid. I was prescribed alendronic acid as my DEXA scan showed mildish osteoporosis when I started arimidex. I think she must have dislodged it, I also have something called GCA which can affect your jaw so I cant say which or if either has caused the problem. Can you keep us posted on whether it goes down again, and if it does whether you or anyone can work out what it is about the drug is causing this to happen and what your doctor suggests when you get to talk to him. Please check with your doctor before stopping taking alendronic acid and switching to alternative treatments. It was the most frightening and totally incomprehensible thing to have no control over my limbs at all but as I sit and write this, I realise it has become totally familiar. Even a couple of paracetamol would make me ill. And of course I was already taking Seroxat, albeit a very small amount. But, remember that without medications, you have to supply your body with enough nutrients and exercise to support and strengthen bone growth. Hello Barbara So, what happens now, does my Osteoporosis get progressively worse over time? It is commonly prescribed to treat patients with bone issues like osteoporosis and Pagets disease. What an awful position to be in! It's harmful if you suddenly stop taking it without a proper assessment from your healthcare provider. She was put on Alendronic acid as she had a fall broke her wrist and has had breast cancer. Taking Prednisone now reduced to 15mg per day and apparently it has accelerated progress of cataracts! I have an appointment at The Royal Dental Practice, Cromwell Road, Dorchster to have two back teeth removed. Warning to anyone who might be taking Alendronic acid 70 ml tablets for osteoporosis ! This was on top of my usual activity levels. But no issue with my teeth. What are we paying the doctors for? Ive just been prescribed AA but having read all the posts on this site have decided not to start taking it. Jan. alendronic acid has destroyed my life I also broke my hip, which made it even more difficult to do anything at all. Stopping and seeing if the symptoms resolve for most drugs is the best way to prove a link some problems with some drugs may take time more time than you expect but will resolve but some may also be permanent. I would say) I was suddenly aware of my mouth being transformed into a state where I was unable to move my lips and then my jaw at all. This was after I had in some detail again described to him how prior to a jerking episode, my muscles pulled tighter and tighter before a violent release .. he metaphorically patted me on the head and told me to go and have a massage. I took the tab yesterday &.the strange & heavy uneven rhythm actually woke me up last night. As I sat up from the bed my head started to pound. if the side effects persist to contact him again Due to Covid you cannot see a GP I asked for a telephone call but was told it would be at least 2 weeks before I could get an appointment Ive decided not to take my more tablets. I dont know if these problems have been caused by the AA, but Im now thinking that I should stop taking it and see if my symptoms resolve. She had to wait months and eventually had the hip replacement. Hey Ive been diagnosed with polymialgia rheumatica too i was prescribed predisolone vit d evacol and now AA Im not having any side effects from it yet but reading all of these comments Im worrying about wether I should take the alendronic acid Ive only taken two up to now but have had no problem with it yet It scares you a bit, Hi I have just been precribed alendronic acid I have not taken it yet as I have had a bad cold. My rheumatologist prescribed AS but I dalayed taking as I had lots of dental work to be done. I compared it with strontium ranelate, which was the drug my sister was taking, and the strontium appeared to have better results. But I just couldnt describe it as you have. Im 62, and fit until I came tumbling of my bicycle 2years ago and damaged my lumbar spine and muscles. This drug is only available for prescription and should be taken with caution. My specialist came back to me a month ago to tell me I should take AA from now on so I started taking the weekly pill 4 weeks ago. She sent me to a specialist for a second opinion and he said take it. It has given me bad acid reflux. . My mother is 83 and has been on this drug for over twenty years with only one bone scan. Alendronic acid | C4H13NO7P2 | CID 2088 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities . Im wondering how you feel now, a year after stopping the drug, have your symptoms improved? Mayo Clinic Press. prevent cancer spreading to the bone. Im 54 years old and after having a Dexa scan, was told that I have Osteoporosis. From day one my tummy was not happy & after 8 weeks I suddenly became severely constipated (Literally overnight !!!) Since things improved I kept taking the medication. I was told that it was very uncommon what happened to me, and it was my choice to take it again next week or not. I also are very intolerant to any meds but my doctor had at last convinced me to trythis and suffice to say I will not be taking any more. Many thanks for all your comments re Alendronic Acid, these have been most helpful in my decision to take this drug. It hurts to walk on my feet. From then on the amount of activity needed to bring on the symptoms became less and less, to where I am now. https://info.mhra.gov.uk/drug-analysis-profiles/dap.html?drug=./UK_EXTERNAL/NONCOMBINED/UK_NON_000837661002.zip&agency=MHRA Hello I am 66 and like many of you am hating taking this drug, I had breast cancer 4 years ago,so am still taking Anastrosil as it was Hormone related,which in turn apparantly helped causing bone density loss, so ws then diagnosed with osteopenia I have osteopenia aged 58 and my sister has osteoporosis aged 65, she was prescribed Alendronic Acid with similar side effects. The method comprises the steps of reacting a compound of formula I with H 3 PO 3 wherein R is an imido group and R 1 is selected from the group consisting of chloro, bromo, iodo, fluoro, hydroxy, amino, OR 2 or OC(O)R 2 , wherein R 2 is C 1 -C 12 alkyl, C 1 -C 12 cycloalkyl or C 1 -C 12 aryl; and then reacting the . Store below 25C. The dentist told me there was no possible way the drugs had anything to do with my teeth getting loose, and it was probably just poor dental hygiene, in spite of the fact that I was 56 when these problems STARTED and 63 when I had to give up and pull the last ones. I have been put on prednisone and even though my bones are ok I have been prescribed AA as prednisone destroys bones. alendronic acid has destroyed my lifealendronic acid has destroyed my life ego service center near me Back to Blog. With this condition, your bones become thin and weak, and break easily. However, below are early signs of osteoporosis: Please see your doctor if your family has a history of osteoporosis to assess your risk. General Warnings. I was such an idiot for believing in this drug! I began to take as prescribed and do not have any problems until 6 days after my 4 th dose, I was awakened in the night with uncomfortable, aching wrists. Side effects include heartburn, upset stomach, nausea, diarrhea and constipation, as well as stomach, muscle, joint and bone pain. It works by slowing down the production of the cells that wear down bone (osteoclasts). Methods: This was a randomised, double-masked, double-dummy multicentre international study (75 centres in 27 countries in . I feel cold inside all the time and the headache is miserable. Ive been prescribed Adcal-D3 tablets (2x twice daily) and Alendronic Acid 1x weekly, even though a blood test showed that my calcium and vitamin D levels were within the normal range. Their non-medical use was to soften water in irrigation systems used in orange groves. In the meantime her teeth fell outliterally fell outwhat on earth was happening. It belongs to a group of drugs called bisphosphonates, which are the most commonly used treatment for people with osteoporosis. Glad Im not alone with these problems,thought i was going mad, hi I had zolondronic infusion no problem ,tablets i cant tolerate so I have hit and missed with them ,I told my consultant and the nurses at the hospital but went unanswered said they would sort it ,five weeks a go I fractured my spine so now Im waiting to see what they going to do Ive been honest with them said i skipped a lot cos I felt sick all the time ,Ive opted for infusion,told them that I did tell them ,but now because Ive fractured my spine Im worried that my bone is bad ,bone density scan and hopefully they will sort infusion out for me .I dont like the tablets,I take vitamin d and c .Im trying to help myself just hope its not too late .wouldnt mind I fell off a ladder about two years ago straight onto my back legs and head fell backwards flat and not a broken bone and I had had a density scan just before the fall. I started reading this because after being diagnosed with breast cancer part of my ongoing treatment is Letrozole plus Alendronic Acid. Below are essential things that you should know before taking alendronic acid: Tell your doctor if you have any dental implants or any tooth issues before taking alendronic acid. Summary Commonly reported side effects of alendronate include: decreased serum calcium and decreased serum phosphate. Do not take this drug if you have mild to severe kidney problems. The NHS say. who told me it could be one of many things. A big thank you to all. Since taking it I have a painful jaw,dry mouth and severe constipation, bloated stomach and a general,feeling of being unwell I spoke to my GP a few weeks ago about my painful jaw and he told me this was quite common and to carry on taking it but. I have been reluctant to start this course of medication due to the possible side effects and negative responses from the enquiries I have made regarding the drug. Were proud to be a team of writers who are truly passionate about all things health.Coming together from all parts of the world, we share a common goal of helping serve many with our comprehensive research and clear writing style. The side effects are bone pain, joint pain and bruising, numbness in the face and lips. The my neck was hurting. Hi, Ive just been reading through some of the comments as I too have concerns over Alendronic acid tablets. I was prescribed Alendronic acid because I had been diagnosed with osteopenia back in 2004. Ive been told to take Allendronicacid. That was the last tablet I took of that drug. Im so sorry to hear your situation and how difficult things are for you. Eventually, I Started Pilates and regular walking. This was before I started checking and researching EVERY drug I was told I needed. Home; About; Program; FAQ; Registration; Sponsorship; Contact; Home; About; Program; FAQ; Registration; Sponsorship . My bloods were fairly normal although my Vit D was just within normal. The doctor put me on ADCAL D3 and alendronic. Delighted to report Tum is behaving much better since giving up just hoping the other side effects ( Jaw and Teeth) dont show up unexpected! So I have decided that it must be the alendronic acid and I have stopped taking them its making my life unbearable. prevent cancer spreading to the bone. It belongs to a class of drugs called bisphosphonates. Ive just discovered that lack of it can be at the root of fatigue, depression, low body temperature, and many other issues. Muscle pain all the time hot sweats but put that down to menapause each time going to doctors about my symptoms only to be told the good will out way the bad Iike hell did it only at the end of july I was walking minding my own business with friends in torquay on holiday 1 day into my holiday I was crossing the road &my leg broke in front of me so I sustained a femur fracture due to AA which has been confirmed twice it was the AA that has caused this I have now come off them my sweats have stopped along with the others symptoms all stopped all off most I put down to a long menapause. Lately, i have been feeling quite unwell, and after having had all sorts of health checks I have now come to the conclusion that my strange symptoms might be due to Alendronic acid. As a follow up to my earlier post, on Feb 21st 2021, I am still experiencing side effects as a result of the ingestion of 1 biphosphonate Alendronic Acid 70g tablet on Sunday Feb 2nd. The bottom of my feet hurt. And yes side effects are happening, muscles ache, jaw aches, I did have an X-ray on my jaw and its fine TG. Given ENEMA which got things moving but still having problems so was referred for COLONOSCOPY!! This pain was far worse than the pain I experience withOsteoporosis! 6.3 Shelf life. My body awareness tells me otherwise. As you age, you will notice changes in your body, such as grayed hair, wrinkles, vision problems, and hearing loss. I cannot say specifically that they have caused me any problems. You would think that and the fact that in Canada a class action suit was brought against the manufacturers of this drug, would be enough to warrant serious alarm bells. Been given Alendronic acid 10mg tablet which I have to take daily. Think Im off to GP to hear her thoughts!!! I am 62, healthy and active. I think its great that we can come in here and discuss how we are feeling. 25 yrs later Ive had a Dexa scan and was told my spine was crumbling and the reading was far worse than the worst possible. Then, you can resume eating and drinking normally. Back to see the same neurologist whose diagnosis this time was that my muscles were very tight so I must be stressed, and if I wasnt already taking it, he would prescribe Seroxat! I had been suffering with a terrible burning tongue for eight months and I also had aching legs, this burning tongue I put down to the gallstones I have got. For a once health, fit woman shes a frail person now who cant walk and has bladder/stomach problems. Hi You should be able to have a dexa scan every 5 years. Whoa, I said, I want to do this with diet and exercise. Now its probable to be loosing my teeth and I live on social security and am very afraid that my dental health has been irrevocably damaged by this drug. The hospital talking about infusions once a year but still waiting for a appointment. Not far into the walk (about 20 mins. On research I found there has been class law suits against the manufacturer of this drug in Canada. It treats osteoporosis in postmenopausal women and men at high risk of fractures. Alendronate is the drug we know as Fosamax. Their mode of action is to disrupt normal bone remodeling, which is ultimately detrimental to bone integrity and fracture resistance. I had open heart surgery at the end of December and didnt take the alendronate for a couple of weeks and coincidentally the swelling went I thought maybe it was caused by fluid build up due to my heart condition and thats why it was better. Angry moment! My doctor didn't mention the gastrointestinal issues when prescribing Alendronic acid and neither did she mention alternative ways of improving my situation. It begins as minor dental problems and can escalate to permanent jaw damage. Want to take back controle before I find myself surrendering myself to more drugs. Your body naturally breaks down old bones and replaces them with new bone tissues to support your skeletal system throughout life. I am 55 years old female and took 1 70mg dose of Alendronic Acid 2 weeks ago after being diagnosed with osteoporosis after a Dexa scan. I have had to keep off coffee, fruit and anything acidic for months, I even tried gaviscon which made me feel sick and had a bloated stomach for 2 hours. All the side effects have calmed down and I feel so much better. Any advice would be greatly appreciated. I am on prednisolone for polymyalgia. I have had 7 weeks off work with a fractured wrist and another week off with feeling poorly due to AA (with no pay as Im a self employed carer) and need to feel fully fit before returning to work. I was wondering if the side effects of the drug actually go away, and if they do, how soon can I expect to see some sort of improvement? A novel process for the preparation of alendronic acid is disclosed. I should have been warned of this side affect. The next day I felt very ill. I have had osteoarthritis for twenty years, and was diagnosed as as having osteopenia 7 years ago. Alendronic acid is used to treat a condition called osteoporosis (brittle bones). Hi everyone.I am new to this forum.I started taking Alendronic acid for the first time yesterday.I have had a bone density scan which shows i have oesteoporosis.I am 59 years old,considered myself quite fit until last June,I have read the side effects of these tablets and what other people have put about them.I am quite scared about taking anymore.I felt fine yesterday after taking mu first . I really think the doctors for whatever reason are unable to tell people to eat right and exercise i.e. I was prescribed Alendronic Acid 70 mg by my GP a couple of months go due to fracturing my humorous after I tripped me fell. Ive only had one tablet of the Alendronic Acid yesterday, but seem to have quite a few of the side effects so wont have another again, and am miffed to see that people have problems for weeks even after one tablet. But its come to my attention that long term , Participants will receive one dose of active zoledronic acid during the first month after heart or liver transplantation and weekly placebo alendronate pills or one dose of placebo zoledronic acid and weekly active alendronate pills for the first year after transplant. I hate taking meds and wonder if I should stop Alendronic acid. They began to itch the next day, ( I took my 5th dose of medication) and they were slightly better but I called my doctor and got in To the office Friday. So if u are on adcal or calcium as well check out it isnt that causing any side effects. Theres little research if alendronic acid is safe for breastfeeding moms. . Hello Claire, I am 60 years old and very modern and active with and without my grandchildren. Hi i have been given AA but couldnt take it due to stomach problems now they are thinking of sending me for infusion could i ask what natural solutions u are using as i was told I couldnt replace bone without AA am very worried about an infusion. Alendronic acid may put your pregnancy at risk. Had another car ride, but then it flared up again, sometimes I limped all morning. I would really welcome views on whether a reading of -4.5 is too high to be able to treat with exercise, diet and supplements. Alendronic acid is not for children or teens below 18 years old. Editorial Note: We want any accounts of adverse or interesting events on drugs or new uses for drugs from people on them or doctors, pharmacists or others trying to manage the effects of drugs. My wrists were swollen, aching. If it is common for headaches, dizzy spells and blackout reportsshouldnt this concern those that live alone, for both GP and patient? She takes Alendronic Acid every week for a year and a half now for her osteoporosis. I do wish you the very best She suggested maybe I stop taking the AS but I already had. My GP suggested that I take another brand but I cannot risk it. When and how you take alendronic acid can affect whether it will work or not. This condition is common in women after the menopause. Pharmaceutical drugs are just about making money and not curing people. I am taking much more care of myself with exercise an I am totally sugar gluten dairy and alcohol free. I also ate one energice bar. 2 years after that I had a dexa test. I hd bone density DXA scan scan in 2010 and was told i had We spoke to the GP & asked if she could come off of Alendronic ,so she did, but now she is having problems with her arms, like a muscle ache. The test showed that I now have osteopenia, but could never get off alendronic as it is due to gluten. She decided to come off the Alendronic AcidShe really has gone downhill. Because of how I tend to react and my blood test results, I thought I would research the new meds first and Im now very pleased that I did.